In 1729, Dr. Johnathan Swift, completely tongue in cheek wrote A Modest Proposal. In 2022, we now know that some people took this entirely too seriously, now selling the unwanted children of the poor for spare parts in the medical community.
Michael Smith published Gay Revolutionary, also a little noticed satire, in Gay Community News, Feb. 15-21, 1987.
I would suggest that by 2015, with the Obergefell decision, and by 2022, with the revelation of large numbers of teachers and preachers and parents actively grooming children for transgenderism, surgery, and now even uterus transplants, that this second satire has also been taken to extremes.